The prevention method of sports medicine imaging modeling / O método preventivo da medicina do esporte no modelo de imagens / El método preventivo de la medicina del deporte en el modelo de imágenes

ABSTRACT Introduction: Sports injury is an important reason to interfere with sports training and physical exercise since it will not only bring unnecessary pain to the injured body, but also bring out negative emotions in athletes. Objective: To study the sports injury characteristics of high level competitive aerobics athletes in China. Methods: Literature data, questionnaire survey, expert interviews, field observation, mathematical statistics and physiotherapy tracking were used. Results: Wrists, ankles, waist and knees were the most frequently injured parts in high level competitive aerobics athletes in China. The main type of injury was acute injury, but chronic injury (48.18%) could not be ignored. Ninety percent of active high-level competitive aerobics athletes train with injuries, and 10 percent of them completely stop training because of injuries. Conclusions: Athletes should pay attention to their physical reserve and strengthen physical training. They must also be attentive to self-supervision, their own subjective feelings, and control the amount of exercise done. Level of evidence II; Therapeutic studies - investigation of treatment results.

RESUMO Introdução: As lesões no esporte são uma razão importante para interferir no treinamento esportivo e no exercício físico, já que não apenas levam a dor desnecessária do corpo lesado, mas também levam a emoções negativas em atletas. Objetivo: Estudar as características de lesões esportivas de atletas de ginástica aeróbica de alto nível competitivo na China. Métodos: Dados da literatura, questionário de sondagem, entrevistas especializadas, observação de campo, estatísticas matemáticas e acompanhamento fisioterapêutico foram usados. Resultados: Pulsos, tornozelos, cintura e joelhos são as partes lesadas com maior frequência nas atletas de ginástica aeróbica de alto nível competitivo na China. O tipo mais comum é a lesão aguda, porém a lesão crônica (48,18%) não pode ser ignorada. Noventa por cento de atletas de ginástica aeróbica de alto nível competitivo na ativa treinam com lesões, e 10% param de treinar completamente devido às lesões. Conclusões: Atletas devem ficar atentos a suas reservas fiscais e fortalecer seu treino físico. Devem também ficar atentos a auto supervisão, ao seu estado emocional e controlar a quantidade exercícios que praticam. Nível de evidência II; Estudos terapêuticos - investigação de resultados de tratamento.

RESUMEN Introducción: Las lesiones en el deporte son una razón importante para interferir en el entrenamiento deportivo y en el ejercicio físico, ya que no solo llevan al dolor desnecesario del cuerpo lesionado, sino que llevan a emociones negativas en atletas. Objetivo: Estudiar las características de lesiones deportivas de atletas de gimnasia aeróbica de alto nivel competitivo en China. Métodos: Se utilizaron datos de la literatura, encuestas de sondeo, entrevistas especializadas, observación de campo, estadísticas matemáticas y acompañamiento fisioterapéutico. Resultados: Muñecas, tobillos, cintura y rodillas son las partes lesionadas con mayor frecuencia en las atletas de gimnasia aeróbica de alto nivel competitivo en China. El tipo más común es la lesión aguda, pero la lesión crónica (48,18%) no puede ignorarse. Noventa por ciento de atletas de gimnasia aeróbica de alto nivel competitivo en China entrenan con lesiones, y 10% paran de entrenar completamiento debido a las lesiones. Conclusiones: Atletas deben atentarse a sus reservas fiscales y fortalecer su entrenamiento físico. Deben también atentarse a la autosupervisión, a su estado emocional y controlar la cantidad de ejercicios que practican. Nivel de evidencia II; Estudios terapéuticos - investigación de resultados de tratamiento.

A feasible classification method of wet masses to predict pellet formation of powdered herbal slices

The aim of the current study was to explore the correlation between physical properties of wet masses and pellet quality by using powdered herbal slices as model drugs. Wet masses with 100 formulations were prepared by taking 20 kinds of powdered herbal slices as model drugs, microcrystalline cellulose as pelletization aid and five levels of added water as liquid binder. Physical properties of the wet masses such as hardness, adhesiveness, springiness, cohesiveness, chewiness, and resilience were measured by a texture analyzer. Meanwhile, the moisture retention capacities (MRC) of powdered herbal slices and wet masses were determined. Particles were classified after they were produced during spheronization. Principal component analysis, factor analysis and classification analysis were performed on the data. Wet masses could be classified into three groups by taking Ha as the first classification index and Ha/Sp as the second classification index. The correct rate of the classification was 91.00%. If Ha value of wet masses was greater than 15610 g, pellets of type ① would form, otherwise, pellets of type ② or type ③ would form based on Ha/Sp value. Then a classification plot of wet masses was developed to predict pellet formation of powdered herbal slices. Meanwhile, the probable mechanism of pellets formation during spheronisation was concluded in this study, which provided useful information to improve pellet quality

Association between bile acid metabolism and bone mineral density in postmenopausal women

OBJECTIVES: Previous studies have not shown any correlation between bile acid metabolism and bone mineral density (BMD) in women with postmenopausal osteoporosis. Thus, the current study evaluated the association between bile acid levels as well as BMD and bone turnover marker levels in this group of women. METHODS: This single-center cross-sectional study included 150 postmenopausal Chinese women. According to BMD, the participants were divided into three groups: osteoporosis group, osteopenia group, and healthy control group. Serum bile acid, fibroblast growth factor 19 (FGF19), and bone turnover biomarker levels were assessed. Moreover, the concentrations of parathyroid hormone, 25-hydroxy vitamin D [25(OH)D], procollagen type I N-peptide (P1NP), and beta-CrossLaps of type I collagen containing cross-linked C-terminal telopeptide (β-CTX) were evaluated. The BMD of the lumbar spine and proximal femur were examined via dual-energy X-ray absorptiometry. RESULTS: The serum total bile acid levels in the osteoporosis and osteopenia groups (5.28±1.56 and 5.31±1.56 umol/L, respectively) were significantly lower than that in the healthy control group (6.33±2.04 umol/L; p=0.002 and 0.018, respectively). Serum bile acid level was positively associated with the BMD of the lumbar spine, femoral neck, and total hip. However, it negatively correlated with β-CTX concentration. Moreover, no correlation was observed between bile acid and P1NP levels, and the levels of the other biomarkers that were measured did not differ between the groups. CONCLUSION: Serum bile acid was positively correlated with BMD and negatively correlated with bone turnover biomarkers reflecting bone absorption in postmenopausal women. Thus, bile acid may play an important role in bone metabolism.

CLINICAL SIGNIFICANCE OF TMAb AND TGAb MEASURED WITH ENZYME-LINKED IMMUNOSORBENT ASSAY / 中华内分泌代谢杂志

The serum thyroid microsomal antibodies (TMAb) and thyroglobulin antibodies (TGAb) were measured in 103 normal persons and 183 patients with different thyroid diseases by enzyme-linked immunosorbent assay (ELISA). The serum T3 and T4 were also tested. The results showed that the incidence of these two autoantibodies were obviously increased in Hashimoto's thyroiditis, hyperthyroidism and hypothyroidism, and normal in simple goiter and thyroid adenoma. The TMAb and TGAb levels in subacute thyroiditis and thyroid cancer were moderately increased. There were also a negative correlation between TMAb and T3, T4, TGAb and T4 in Hashimoto's thyroiditis.

Thyroid microsomal antigen-antibody system and its clinical significance / 中国免疫学杂志

Thyroid microsomal antigen-antibody(TMAg-Ab)system plays an important role in the pathogenesis of autoimmune thyroid diseases.TMAb are involved in the complementmediated cytotoxicity and antibody-dependent cytotoxicity,resulting in thyroid follicle epithelial cell and basement membrane injury,followed by thyroiditis and hypothyroidism,and they may also cause hyperthyroidism through some unknown mechanisms.In recent years,indirect hemagglutination,radioimmunoassay and enzyme-inked immunosorbent assay have been used to detect TMAb in thyroid disease patients'sera,indicating the incidence as high as 90%.Measurements of T3,T4 and TSH alsoreveal that serum TMAb level is related with the variation of T3,T4 and TSH.It ispostulated that TMAg might be the lipoprotein on smooth endoplasmic reticulum ofthyroid follicle epithelial cell.Due to the difficulties to purify TMAg,its nature stillremains unclear.